• Angiogenesis

  • Src

  • FLT3

  • VDA

  • HIF

  • FGFR

  • Syk

  • FAK

  • BTK

• Apoptosis

  • Bcl-2

  • TNF-alpha

  • Mdm2

  • Survivin

  • p53

  • Caspase

  • IAP

  • PERK

• Autophagy
• Cell Cycle

  • Aurora Kinase

  • ROCK

  • PLK

  • CDK

  • Rho

  • Wee1

  • Chk

  • APC

  • c-Myc

• Cytoskeletal Signaling

  • HSP (e.g. HSP90)

  • Microtubule Associated

  • Kinesin

  • PAK

• DNA Damage

  • PARP

  • ATM/ATR

  • DNA/RNA Synthesis

  • Telomerase

  • Topoisomerase

  • PPAR

  • DNA-PK

• Endocrinology & Hormones

  • Androgen Receptor

  • Aromatase

  • Estrogen/progestogen Receptor

  • 5-alpha Reductase

  • RAAS

  • GPR

• Epigenetics

  • HDAC

  • Sirtuin

  • DNA Methyltransferase

  • Epigenetic Reader Domain

  • Histone Methyltransferase

  • Histone demethylases

  • Histone Acetyltransferase

• GPCR & G Protein

  • S1P Receptor

  • MT Receptor

  • CaSR

  • LPA Receptor

  • PAFR

  • Endothelin Receptor

  • Cannabinoid Receptor

  • CGRP Receptor

  • OX Receptor

  • SGLT

  • Adenosine Receptor

  • cAMP

  • Vasopressin Receptor

  • CXCR

  • Protease-Activated Receptor

  • Prostaglandin Receptor

• JAK/STAT

  • JAK

  • STAT

  • Pim

• MAPK

  • MEK

  • p38 MAPK

  • Raf

  • JNK

  • ERK

• Metabolism

  • Factor Xa

  • Phospholipase (e.g. PLA)

  • P450 (e.g. CYP17)

  • DHFR

  • PDE

  • Carbonic Anhydrase

  • Hydroxylase

  • Dehydrogenase

  • Transferase

  • MAO

  • Aminopeptidase

  • HMG-CoA Reductase

  • Procollagen C Proteinase

  • FAAH

  • Phosphorylase

  • CETP

  • IDO

  • Ferroptosis

• Microbiology

  • Integrase

  • CCR

  • Reverse Transcriptase

• Neuronal Signaling

  • GluR

  • Opioid Receptor

  • GABA Receptor

  • Adrenergic Receptor

  • 5-HT Receptor

  • P2 Receptor

  • COX

  • Dopamine Receptor

  • AMPA Receptor-kainate Receptor-NMDA Receptor

  • AChR

  • Histamine Receptor

  • Beta Amyloid

• NF-κB Signaling

  • IκB/IKK

  • NOD1

  • NF-κB

• PI3K/Akt/mTOR

  • PI3K

  • mTOR

  • Akt

  • GSK-3

  • PDK-1

  • PKA

  • AMPK

  • S6 Kinase

• Proteases

  • Proteasome

  • DPP-4

  • Cysteine Protease

  • HCV Protease

  • HIV Protease

  • Gamma-secretase

  • BACE

  • MMP

  • DUB

  • Serine Protease

• Protein Tyrosine Kinase

  • VEGFR

  • EGFR

  • IGF-1R

  • Bcr-Abl

  • HER2

  • PDGFR

  • c-Kit

  • c-Met

  • ALK

  • Tie-2

  • Ephrin receptor

  • Axl

  • Trk receptor

  • CSF-1R

• Stem Cells & Wnt

  • Hedgehog/Smoothened

  • Wnt/beta-catenin

• TGF-beta/Smad Signaling

  • PKC

  • TGF-beta/Smad

• Transmembrane Transporters

  • CFTR

  • Sodium Channel

  • Calcium Channel

  • Proton Pump

  • Potassium Channel

  • ATPase

  • P-gp

  • CRM1

• Ubiquitin

  • E3 Ligase

  • p97

  • E1 Activating

  • E2 conjugating

  • Deubiquitinase

• Others

  • Substance P

  • IL Receptor

  • Lysyl Hydroxylase

  • Thrombin

  • Liver X Receptor

  • gp120/CD4

  • FXR

  • TRPV

  • Integrin

  • Dynamin

  • Other inhibitors