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propanoic acid,3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
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propanoic acid,3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
Propanoic acid,3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
CAS:68181-17-9 分子式:C12H12N2O4S2 分子量:312.36468
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产品名称:Succinimidyl 3-​[(2-​pyridyl)​dithio]​propionate; Succinimidyl 3-​[[(2-​pyridyl)​thio]​thio]​propionate
其他名称:SPDP; SPDP-​Osu;N-​Succinimidyl 3-​(pyridyldithio)​propionate
CAS:68181-17-9
结构信息
分子式 C12H12N2O4S2 分子量 312.36468
性状照片  
性质说明
1) 可溶于DMF、DMSO等
2) 室温密封保存
合成应用
1) 可用于交联剂
表征图谱
HNMR
NA
MS
NA
FTIR
NA
HPLC
NA
参考文献
1) Carlsson J; Drevin H; Axen R; The Biochemical journal 1978, 173(3), 723-737, Protein thiolation and reversible protein-​protein conjugation. N-​Succinimidyl 3-​(2-​pyridyldithio)​propionate, a new heterobifunctional reagent
2) Clarke, James; Wu, Hai-Chen; Jayasinghe, Lakmal; Patel, Alpesh; Reid, Stuart; Bayley, Hagan; Nature Nanotechnology 2009, 4(4), 265-270, DOI: 10.1038/nnano.2009.12 ; Continuous base identification for single-​molecule nanopore DNA sequencing
3) Wagner, Ernst; Zenke, Martin; Cotten, Matt; Beug, Hartmut; Birnstiel, Max L.; Proceedings of the National Academy of Sciences of the United States of America 1990, 87(9), 3410-3414, DOI: 10.1073/pnas.87.9.3410 ; Transferrin-​polycation conjugates as carriers for DNA uptake into cells
4) Miyata, Kanjiro; Kakizawa, Yoshinori; Nishiyama, Nobuhiro; Harada, Atsushi; Yamasaki, Yuichi; Koyama, Hiroyuki; Kataoka, Kazunori; Journal of the American Chemical Society 2004, 126(8), 2355-2361, DOI: 10.1021/ja0379666 ; Block catiomer polyplexes with regulated densities of charge and disulfide cross-​linking directed to enhance gene expression

5) Josephson, Lee; Kircher, Moritz F.; Mahmood, Umar; Tang, Yi; Weissleder, Ralph; Bioconjugate Chemistry 2002, 13(3), 554-560, DOI: 10.1021/bc015555d ; Near-​Infrared Fluorescent Nanoparticles as Combined MR​/Optical Imaging Probes

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propanoic acid,3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
propanoic acid,3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester