产品名称:Tetramethylenedimaleimide其他名称:BMB Crosslinker;1,1'-(1,4-Butanediyl)bis[1H-pyrrole-2,5-dione]; 1,4-Bis(maleimide)butane; 1,4-Bis(maleimido)butane; 1,4-Di(maleimido)butane; 1-[4-(2,5-Dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione; N,N'-1,4-Butylenebismaleimide; N,N'-Tetramethylenebis[maleimide]; N,N'-Tetramethylenedimaleimide; Tetramethylenebismaleimide; CAS:28537-70-4
结构信息
分子式 |
C12H12N2O4 |
分子量 |
248.23468 |
性状照片 |
|
性质说明
1) 可溶于DMF、DMSO等
2) 室温密封保存
合成应用
1) 可用于交联剂
表征图谱
参考文献
1) Feast, William J.; Put, J.; De Schryver, F. C.; Compernolle, F. C.; Organic Mass Spectrometry 1970, 3(4), 507-517, DOI: 10.1002/oms.1210030408 ; Mass spectra of maleimides, isomaleimides, bis-maleimides, bis-isomaleimides and the intramolecular photocyclization products of bis-maleimides
2) Matuszak, Nicolas; Muccioli, Giulio G.; Labar, Geoffray; Lambert, Didier M.; J. Med. Chem. 2009, 52(23), 7410-7420, DOI: 10.1021/jm900461w ; Synthesis and in Vitro Evaluation of N-Substituted Maleimide Derivatives as Selective Monoglyceride Lipase Inhibitors
3) Green, Nora S.; Reisler, Emil; Houk, K. N.; Protein Science 2001, 10(7), 1293-1304, DOI: 10.1110/ps.51201 ; Quantitative evaluation of the lengths of homobifunctional protein cross-linking reagents used as molecular rulers
4) Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; Duggan, Matthew J.; Loy, Sharon D.; Bonham, Kathryn A.; Blodgett, James K.; J. Med. Chem. 1992, 35(9), 1563-1572, DOI: 10.1021/jm00087a010 ; A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers