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1,4-双(马来酰亚胺基)丁烷
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1,4-双(马来酰亚胺基)丁烷
1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione)
CAS:28537-70-4 分子式:C12H12N2O4 分子量:248.23468
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产品名称:Tetramethylenedimale​imide
其他名称:BMB Crosslinker;1,​1'-​(1,​4-​Butanediyl)​bis[1H-​pyrrole-​2,​5-​dione]​; 1,​4-​Bis(maleimide)​butane; 1,​4-​Bis(maleimido)​butane; 1,​4-​Di(maleimido)​butane; 1-​[4-​(2,​5-​Dioxopyrrol-​1-​yl)​butyl]​pyrrole-​2,​5-​dione; N,​N'-​1,​4-​Butylenebismaleimide​; N,​N'-​Tetramethylenebis[ma​leimide]​; N,​N'-​Tetramethylenedimale​imide; Tetramethylenebismal​eimide;
CAS:28537-70-4
结构信息
分子式 C12H12N2O4 分子量 248.23468
性状照片  
性质说明
1) 可溶于DMF、DMSO等
2) 室温密封保存
合成应用
1) 可用于交联剂
表征图谱
HNMR
NA
MS
NA
FTIR
NA
HPLC
NA
参考文献
1) Feast, William J.; Put, J.; De Schryver, F. C.; Compernolle, F. C.; Organic Mass Spectrometry 1970, 3(4), 507-517, DOI: 10.1002/oms.1210030408 ; Mass spectra of maleimides, isomaleimides, bis-​maleimides, bis-​isomaleimides and the intramolecular photocyclization products of bis-​maleimides
2) Matuszak, Nicolas; Muccioli, Giulio G.; Labar, Geoffray; Lambert, Didier M.; J. Med. Chem. 2009, 52(23), 7410-7420, DOI: 10.1021/jm900461w ; Synthesis and in Vitro Evaluation of N-​Substituted Maleimide Derivatives as Selective Monoglyceride Lipase Inhibitors
3) Green, Nora S.; Reisler, Emil; Houk, K. N.; Protein Science 2001, 10(7), 1293-1304, DOI: 10.1110/ps.51201 ; Quantitative evaluation of the lengths of homobifunctional protein cross-​linking reagents used as molecular rulers
4) Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; Duggan, Matthew J.; Loy, Sharon D.; Bonham, Kathryn A.; Blodgett, James K.; J. Med. Chem. 1992, 35(9), 1563-1572, DOI: 10.1021/jm00087a010 ; A new class of bradykinin antagonists:  synthesis and in vitro activity of bissuccinimidoalkane peptide dimers

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1,4-双(马来酰亚胺基)丁烷
1,4-双(马来酰亚胺基)丁烷